Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

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Abstract

<p> <p id="x-x-__p1"> Oculogyric crisis is a rare ocular dystonia first appearing at the turn of the last century in postencephalitic patients. In the modern era, they were most frequently associated with first-generation D1 dopaminergic receptor blocking antipsychotic medication. <p id="x-x-__p2"> We present an unusual case of acute oculogyric crisis in a 74-year-old woman with long-standing Parkinson disease following exposure to the second-generation neuroleptic ziprasidone, which has dopaminergic (D2) and serotoninergic (5-HT2A) receptor blocking effects and is used for severe delusions and psychosis. To the best of our knowledge, there are no other published reports. <strong> Keywords: </strong> ziprasidone, oculogyric crisis, acute dystonia </p> </p></p>
Original languageAmerican English
JournalCureus
Volume12
StatePublished - Jul 9 2020

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