Transplantation of a genetically modified porcine heart into a live human

Bartley P. Griffith; Alison Grazioli; Avneesh K. Singh; Andy Tully; Javier Galindo; Kapil K. Saharia; Aakash Shah; Erik R. Strauss; Patrick N. Odonkor; Brittney Williams; Henry J. Silverman; Allen Burke; Cinthia B. Drachenberg; Chris L. Wells; Timm Dickfeld; Susie N. Hong; Albert J. Hicks; Manjula Ananthram; Anuj Gupta; Robert H. Christenson; Lo Tamburro; Tianshu Zhang; Alena Hershfeld; Billeta Lewis; Erika D. Feller; Kasinath Kuravi; Lori Sorrells; Erwan Morgand; Fariza Mezine; Valentin Goutaudier; Martine Rothblatt; Christine L. Lau; Bradley Taylor; Steve Perrin; Alexandre Loupy; David Ayares; Muhammad M. Mohiuddin

doi:10.1038/s41591-024-03429-1

Transplantation of a genetically modified porcine heart into a live human

Bartley P. Griffith
, Alison Grazioli
, Avneesh K. Singh
, Andy Tully
, Javier Galindo
, Kapil K. Saharia
, Aakash Shah
, Erik R. Strauss
, Patrick N. Odonkor
, Brittney Williams
, Henry J. Silverman
, Allen Burke
, Cinthia B. Drachenberg
, Chris L. Wells
, Timm Dickfeld
, Susie N. Hong
, Albert J. Hicks
, Manjula Ananthram
, Anuj Gupta
, Robert H. Christenson

Lo Tamburro, Tianshu Zhang, Alena Hershfeld, Billeta Lewis, Erika D. Feller, Kasinath Kuravi, Lori Sorrells, Erwan Morgand, Fariza Mezine, Valentin Goutaudier, Martine Rothblatt, Christine L. Lau, Bradley Taylor, Steve Perrin, Alexandre Loupy, David Ayares, Muhammad M. Mohiuddin

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e12744
Pages (from-to)	589-598
Number of pages	10
Journal	Nature medicine
Volume	31
Issue number	2
DOIs	https://doi.org/10.1038/s41591-024-03429-1
State	Published - Feb 2025
Externally published	Yes

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

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10.1038/s41591-024-03429-1

Cite this

Griffith, B. P., Grazioli, A., Singh, A. K., Tully, A., Galindo, J., Saharia, K. K., Shah, A., Strauss, E. R., Odonkor, P. N., Williams, B., Silverman, H. J., Burke, A., Drachenberg, C. B., Wells, C. L., Dickfeld, T., Hong, S. N., Hicks, A. J., Ananthram, M., Gupta, A., ... Mohiuddin, M. M. (2025). Transplantation of a genetically modified porcine heart into a live human. Nature medicine, 31(2), 589-598. Article e12744. https://doi.org/10.1038/s41591-024-03429-1

Griffith, BP, Grazioli, A, Singh, AK, Tully, A, Galindo, J, Saharia, KK, Shah, A, Strauss, ER, Odonkor, PN, Williams, B, Silverman, HJ, Burke, A, Drachenberg, CB, Wells, CL, Dickfeld, T, Hong, SN, Hicks, AJ, Ananthram, M, Gupta, A, Christenson, RH, Tamburro, L, Zhang, T, Hershfeld, A, Lewis, B, Feller, ED, Kuravi, K, Sorrells, L, Morgand, E, Mezine, F, Goutaudier, V, Rothblatt, M, Lau, CL, Taylor, B, Perrin, S, Loupy, A, Ayares, D & Mohiuddin, MM 2025, 'Transplantation of a genetically modified porcine heart into a live human', Nature medicine, vol. 31, no. 2, e12744, pp. 589-598. https://doi.org/10.1038/s41591-024-03429-1

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title = "Transplantation of a genetically modified porcine heart into a live human",

author = "Griffith, \{Bartley P.\} and Alison Grazioli and Singh, \{Avneesh K.\} and Andy Tully and Javier Galindo and Saharia, \{Kapil K.\} and Aakash Shah and Strauss, \{Erik R.\} and Odonkor, \{Patrick N.\} and Brittney Williams and Silverman, \{Henry J.\} and Allen Burke and Drachenberg, \{Cinthia B.\} and Wells, \{Chris L.\} and Timm Dickfeld and Hong, \{Susie N.\} and Hicks, \{Albert J.\} and Manjula Ananthram and Anuj Gupta and Christenson, \{Robert H.\} and Lo Tamburro and Tianshu Zhang and Alena Hershfeld and Billeta Lewis and Feller, \{Erika D.\} and Kasinath Kuravi and Lori Sorrells and Erwan Morgand and Fariza Mezine and Valentin Goutaudier and Martine Rothblatt and Lau, \{Christine L.\} and Bradley Taylor and Steve Perrin and Alexandre Loupy and David Ayares and Mohiuddin, \{Muhammad M.\}",

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month = feb,

doi = "10.1038/s41591-024-03429-1",

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AU - Griffith, Bartley P.

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AU - Singh, Avneesh K.

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AU - Galindo, Javier

AU - Saharia, Kapil K.

AU - Shah, Aakash

AU - Strauss, Erik R.

AU - Odonkor, Patrick N.

AU - Williams, Brittney

AU - Silverman, Henry J.

AU - Burke, Allen

AU - Drachenberg, Cinthia B.

AU - Wells, Chris L.

AU - Dickfeld, Timm

AU - Hong, Susie N.

AU - Hicks, Albert J.

AU - Ananthram, Manjula

AU - Gupta, Anuj

AU - Christenson, Robert H.

AU - Tamburro, Lo

AU - Zhang, Tianshu

AU - Hershfeld, Alena

AU - Lewis, Billeta

AU - Feller, Erika D.

AU - Kuravi, Kasinath

AU - Sorrells, Lori

AU - Morgand, Erwan

AU - Mezine, Fariza

AU - Goutaudier, Valentin

AU - Rothblatt, Martine

AU - Lau, Christine L.

AU - Taylor, Bradley

AU - Perrin, Steve

AU - Loupy, Alexandre

AU - Ayares, David

AU - Mohiuddin, Muhammad M.

PY - 2025/2

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Transplantation of a genetically modified porcine heart into a live human

ASJC Scopus Subject Areas

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