The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases

Paul W. Sperduto; T. Jonathan Yang; Kathryn Beal; Hubert Pan; Paul D. Brown; Ananta Bangdiwala; Ryan Shanley; Norman Yeh; Laurie E. Gaspar; Steve Braunstein; Penny Sneed; John Boyle; John P. Kirkpatrick; Kimberley S. Mak; Helen A. Shih; Alex Engelman; David Roberge; Nils D. Arvold; Brian Alexander; Mark M. Awad; Joseph Contessa; Veronica Chiang; John Hardie; Daniel Ma; Emil Lou; William Sperduto; Minesh P. Mehta

doi:10.1016/j.ijrobp.2016.06.006

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases

Paul W. Sperduto, T. Jonathan Yang, Kathryn Beal, Hubert Pan, Paul D. Brown, Ananta Bangdiwala, Ryan Shanley, Norman Yeh, Laurie E. Gaspar, Steve Braunstein, Penny Sneed, John Boyle, John P. Kirkpatrick, Kimberley S. Mak, Helen A. Shih, Alex Engelman, David Roberge, Nils D. Arvold, Brian Alexander, Mark M. AwadJoseph Contessa, Veronica Chiang, John Hardie, Daniel Ma, Emil Lou, William Sperduto, Minesh P. Mehta

Miami Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	International Journal of Radiation Oncology Biology Physics
Volume	96
DOIs	https://doi.org/10.1016/j.ijrobp.2016.06.006
State	Published - Jan 10 2016

Disciplines

Pathology
Medicine and Health Sciences
Endocrinology
Surgery

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Sperduto, P. W., Yang, T. J., Beal, K., Pan, H., Brown, P. D., Bangdiwala, A., Shanley, R., Yeh, N., Gaspar, L. E., Braunstein, S., Sneed, P., Boyle, J., Kirkpatrick, J. P., Mak, K. S., Shih, H. A., Engelman, A., Roberge, D., Arvold, N. D., Alexander, B., ... Mehta, M. P. (2016). The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. International Journal of Radiation Oncology Biology Physics, 96. https://doi.org/10.1016/j.ijrobp.2016.06.006

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases. / Sperduto, Paul W.; Yang, T. Jonathan; Beal, Kathryn et al.
In: International Journal of Radiation Oncology Biology Physics, Vol. 96, 10.01.2016.

Research output: Contribution to journal › Article › peer-review

Sperduto, PW, Yang, TJ, Beal, K, Pan, H, Brown, PD, Bangdiwala, A, Shanley, R, Yeh, N, Gaspar, LE, Braunstein, S, Sneed, P, Boyle, J, Kirkpatrick, JP, Mak, KS, Shih, HA, Engelman, A, Roberge, D, Arvold, ND, Alexander, B, Awad, MM, Contessa, J, Chiang, V, Hardie, J, Ma, D, Lou, E, Sperduto, W & Mehta, MP 2016, 'The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases', International Journal of Radiation Oncology Biology Physics, vol. 96. https://doi.org/10.1016/j.ijrobp.2016.06.006

@article{34b93c857534458198b5f1413dcca9cd,

title = "The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases",

author = "Sperduto, {Paul W.} and Yang, {T. Jonathan} and Kathryn Beal and Hubert Pan and Brown, {Paul D.} and Ananta Bangdiwala and Ryan Shanley and Norman Yeh and Gaspar, {Laurie E.} and Steve Braunstein and Penny Sneed and John Boyle and Kirkpatrick, {John P.} and Mak, {Kimberley S.} and Shih, {Helen A.} and Alex Engelman and David Roberge and Arvold, {Nils D.} and Brian Alexander and Awad, {Mark M.} and Joseph Contessa and Veronica Chiang and John Hardie and Daniel Ma and Emil Lou and William Sperduto and Mehta, {Minesh P.}",

note = "Purpose Lung cancer remains the most common cause of both cancer mortality and brain metastases (BM). The purpose of this study was to assess the effect of gene alterations and tyrosine kinase inhibition (TKI) on median survival (MS) and cause of death (CoD) in patients with BM from lung adenocarcinoma (L-adeno).",

year = "2016",

month = jan,

day = "10",

doi = "10.1016/j.ijrobp.2016.06.006",

language = "American English",

volume = "96",

journal = "International Journal of Radiation Oncology Biology Physics",

}

TY - JOUR

T1 - The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases

AU - Sperduto, Paul W.

AU - Yang, T. Jonathan

AU - Beal, Kathryn

AU - Pan, Hubert

AU - Brown, Paul D.

AU - Bangdiwala, Ananta

AU - Shanley, Ryan

AU - Yeh, Norman

AU - Gaspar, Laurie E.

AU - Braunstein, Steve

AU - Sneed, Penny

AU - Boyle, John

AU - Kirkpatrick, John P.

AU - Mak, Kimberley S.

AU - Shih, Helen A.

AU - Engelman, Alex

AU - Roberge, David

AU - Arvold, Nils D.

AU - Alexander, Brian

AU - Awad, Mark M.

AU - Contessa, Joseph

AU - Chiang, Veronica

AU - Hardie, John

AU - Ma, Daniel

AU - Lou, Emil

AU - Sperduto, William

AU - Mehta, Minesh P.

N1 - Purpose Lung cancer remains the most common cause of both cancer mortality and brain metastases (BM). The purpose of this study was to assess the effect of gene alterations and tyrosine kinase inhibition (TKI) on median survival (MS) and cause of death (CoD) in patients with BM from lung adenocarcinoma (L-adeno).

PY - 2016/1/10

Y1 - 2016/1/10

UR - https://mayoclinic.pure.elsevier.com/en/publications/the-effect-of-gene-alterations-and-tyrosine-kinase-inhibition-on-

U2 - 10.1016/j.ijrobp.2016.06.006

DO - 10.1016/j.ijrobp.2016.06.006

M3 - Article

VL - 96

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

ER -

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases

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