Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases

Shireen Parsai; Jaco Miller; Aditya Juloori; Samuel T Chao; Rupesh Kotecha; Alireza M Mohammadi; Manmeet Ahluwalia; A. S Murphy; Gene H Barnet; Michael A Vogelbaum; Lilyana Angelov; David M Peereboom; John H Suh

Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases

Shireen Parsai
, Jaco Miller
, Aditya Juloori
, Samuel T Chao
, Rupesh Kotecha
, Alireza M Mohammadi
, Manmeet Ahluwalia
, A. S Murphy
, Gene H Barnet
, Michael A Vogelbaum
, Lilyana Angelov
, David M Peereboom
, John H Suh

Miami Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Neurosurgery
Volume	132
State	Published - Feb 8 2019

Disciplines

Medicine and Health Sciences

Cite this

@article{f26bc7be7dad4308b919695066307a02,

title = "Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases",

author = "Shireen Parsai and Jaco Miller and Aditya Juloori and Chao, \{Samuel T\} and Rupesh Kotecha and Mohammadi, \{Alireza M\} and Manmeet Ahluwalia and Murphy, \{A. S\} and Barnet, \{Gene H\} and Vogelbaum, \{Michael A\} and Lilyana Angelov and Peereboom, \{David M\} and Suh, \{John H\}",

note = "For patients with HER2+ breast cancer brain metastases, the use of lapatinib concurrently with SRS improved local control of brain metastases, without an increased rate of radiation necrosis. Concurrent lapatinib best augments the efficacy of SRS for lesions ≤ 1.10 cm3 in volume. In patients who und ...",

year = "2019",

month = feb,

day = "8",

language = "American English",

volume = "132",

journal = "Journal of Neurosurgery",

}

TY - JOUR

T1 - Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases

AU - Parsai, Shireen

AU - Miller, Jaco

AU - Juloori, Aditya

AU - Chao, Samuel T

AU - Kotecha, Rupesh

AU - Mohammadi, Alireza M

AU - Ahluwalia, Manmeet

AU - Murphy, A. S

AU - Barnet, Gene H

AU - Vogelbaum, Michael A

AU - Angelov, Lilyana

AU - Peereboom, David M

AU - Suh, John H

N1 - For patients with HER2+ breast cancer brain metastases, the use of lapatinib concurrently with SRS improved local control of brain metastases, without an increased rate of radiation necrosis. Concurrent lapatinib best augments the efficacy of SRS for lesions ≤ 1.10 cm3 in volume. In patients who und ...

PY - 2019/2/8

Y1 - 2019/2/8

UR - https://pubmed.ncbi.nlm.nih.gov/30738402/

M3 - Article

VL - 132

JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

ER -

Stereotactic radiosurgery with concurrent lapatinib is associated with improved local control for HER2-positive breast cancer brain metastases

Disciplines

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