Remission of 
        TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).

Guenther Koehne; Muhammad U Mushtaq; Lori S Muffly; Manuel Menes; Jacques Azzi; Lea Bernard; Brenda Cooper; Vanessa Kennedy; Divya Koura; Joseph Maakaron; John Magenau; Brian McClune; Sagar S Patel; Joseph C Rimando; Nirali N Shah; Hyung C Suh; Roni Tamari; Sanjana Thosar; Giacomo Canesin; Sharon L Hyzy; Melissa M Lee-Sundlov; Darren A Stanizzi; Diana Hummel; Michelle I Lin; Glen D Raffel; Jennifer S Whangbo; John F DiPersio

doi:10.1200/PO-25-00556

Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).

Guenther Koehne
, Muhammad U Mushtaq
, Lori S Muffly
, Manuel Menes
, Jacques Azzi
, Lea Bernard
, Brenda Cooper
, Vanessa Kennedy
, Divya Koura
, Joseph Maakaron
, John Magenau
, Brian McClune
, Sagar S Patel
, Joseph C Rimando
, Nirali N Shah
, Hyung C Suh
, Roni Tamari
, Sanjana Thosar
, Giacomo Canesin
, Sharon L Hyzy

Melissa M Lee-Sundlov, Darren A Stanizzi, Diana Hummel, Michelle I Lin, Glen D Raffel, Jennifer S Whangbo, John F DiPersio

Herbert Wertheim Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	e2500556
Journal	JCO precision oncology
Volume	9
DOIs	https://doi.org/10.1200/PO-25-00556
State	Published - Oct 2025

Access to Document

10.1200/PO-25-00556

Cite this

Koehne, G., Mushtaq, M. U., Muffly, L. S., Menes, M., Azzi, J., Bernard, L., Cooper, B., Kennedy, V., Koura, D., Maakaron, J., Magenau, J., McClune, B., Patel, S. S., Rimando, J. C., Shah, N. N., Suh, H. C., Tamari, R., Thosar, S., Canesin, G., ... DiPersio, J. F. (2025). Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33). JCO precision oncology, 9, e2500556. https://doi.org/10.1200/PO-25-00556

Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33). / Koehne, Guenther; Mushtaq, Muhammad U; Muffly, Lori S et al.
In: JCO precision oncology, Vol. 9, 10.2025, p. e2500556.

Research output: Contribution to journal › Article › peer-review

Koehne, G, Mushtaq, MU, Muffly, LS, Menes, M, Azzi, J, Bernard, L, Cooper, B, Kennedy, V, Koura, D, Maakaron, J, Magenau, J, McClune, B, Patel, SS, Rimando, JC, Shah, NN, Suh, HC, Tamari, R, Thosar, S, Canesin, G, Hyzy, SL, Lee-Sundlov, MM, Stanizzi, DA, Hummel, D, Lin, MI, Raffel, GD, Whangbo, JS & DiPersio, JF 2025, 'Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).', JCO precision oncology, vol. 9, pp. e2500556. https://doi.org/10.1200/PO-25-00556

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title = "Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).",

author = "Guenther Koehne and Mushtaq, \{Muhammad U\} and Muffly, \{Lori S\} and Manuel Menes and Jacques Azzi and Lea Bernard and Brenda Cooper and Vanessa Kennedy and Divya Koura and Joseph Maakaron and John Magenau and Brian McClune and Patel, \{Sagar S\} and Rimando, \{Joseph C\} and Shah, \{Nirali N\} and Suh, \{Hyung C\} and Roni Tamari and Sanjana Thosar and Giacomo Canesin and Hyzy, \{Sharon L\} and Lee-Sundlov, \{Melissa M\} and Stanizzi, \{Darren A\} and Diana Hummel and Lin, \{Michelle I\} and Raffel, \{Glen D\} and Whangbo, \{Jennifer S\} and DiPersio, \{John F\}",

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AU - Cooper, Brenda

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AU - Magenau, John

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AU - Patel, Sagar S

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AU - Suh, Hyung C

AU - Tamari, Roni

AU - Thosar, Sanjana

AU - Canesin, Giacomo

AU - Hyzy, Sharon L

AU - Lee-Sundlov, Melissa M

AU - Stanizzi, Darren A

AU - Hummel, Diana

AU - Lin, Michelle I

AU - Raffel, Glen D

AU - Whangbo, Jennifer S

AU - DiPersio, John F

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