Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.

Michael D Prados; David A Larson; Kathleen Lamborn; Michael W McDermott; Penny K Sneed; William M Wara; Susan M Chang; Ellen E Mack; Hendrikus G.J Krouwer; Kym L Chandler; Ronald E Warnick; Richard L Davis; R N Jane E Rabbitt; B A Mary Malec; Victor A Levin; Phillip H Gutin; Theodore L Phillips; Charles B Wilson

doi:10.1016/S0360-3016(97)00566-X

Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.

Michael D Prados, David A Larson, Kathleen Lamborn, Michael W McDermott, Penny K Sneed, William M Wara, Susan M Chang, Ellen E Mack, Hendrikus G.J Krouwer, Kym L Chandler, Ronald E Warnick, Richard L Davis, R N Jane E Rabbitt, B A Mary Malec, Victor A Levin, Phillip H Gutin, Theodore L Phillips, Charles B Wilson

Miami Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	International Journal of Radiation Oncology Biology Physics
Volume	40
DOIs	https://doi.org/10.1016/S0360-3016(97)00566-X
State	Published - Jan 1 1998

Disciplines

Survival Analysis
Urology
Medicine and Health Sciences
Other Medical Specialties

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Prados, M. D., Larson, D. A., Lamborn, K., McDermott, M. W., Sneed, P. K., Wara, W. M., Chang, S. M., Mack, E. E., Krouwer, H. G. J., Chandler, K. L., Warnick, R. E., Davis, R. L., Rabbitt, R. N. J. E., Malec, B. A. M., Levin, V. A., Gutin, P. H., Phillips, T. L., & Wilson, C. B. (1998). Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors. International Journal of Radiation Oncology Biology Physics, 40. https://doi.org/10.1016/S0360-3016(97)00566-X

Prados, MD, Larson, DA, Lamborn, K, McDermott, MW, Sneed, PK, Wara, WM, Chang, SM, Mack, EE, Krouwer, HGJ, Chandler, KL, Warnick, RE, Davis, RL, Rabbitt, RNJE, Malec, BAM, Levin, VA, Gutin, PH, Phillips, TL & Wilson, CB 1998, 'Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.', International Journal of Radiation Oncology Biology Physics, vol. 40. https://doi.org/10.1016/S0360-3016(97)00566-X

@article{d8cd4b6962044e70a84e5c6d3632a994,

title = "Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.",

author = "Prados, {Michael D} and Larson, {David A} and Kathleen Lamborn and McDermott, {Michael W} and Sneed, {Penny K} and Wara, {William M} and Chang, {Susan M} and Mack, {Ellen E} and Krouwer, {Hendrikus G.J} and Chandler, {Kym L} and Warnick, {Ronald E} and Davis, {Richard L} and Rabbitt, {R N Jane E} and Malec, {B A Mary} and Levin, {Victor A} and Gutin, {Phillip H} and Phillips, {Theodore L} and Wilson, {Charles B}",

note = "This therapy was no more effective in patients with GBM than other reported series. In patients with malignant gliomas other than GBM, prolonged progression-free and overall survival is noted, without a median survival reached at the time of this report. In this subset of AG patients, survival is co ...",

year = "1998",

month = jan,

day = "1",

doi = "10.1016/S0360-3016(97)00566-X",

language = "American English",

volume = "40",

journal = "International Journal of Radiation Oncology Biology Physics",

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TY - JOUR

T1 - Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.

AU - Prados, Michael D

AU - Larson, David A

AU - Lamborn, Kathleen

AU - McDermott, Michael W

AU - Sneed, Penny K

AU - Wara, William M

AU - Chang, Susan M

AU - Mack, Ellen E

AU - Krouwer, Hendrikus G.J

AU - Chandler, Kym L

AU - Warnick, Ronald E

AU - Davis, Richard L

AU - Rabbitt, R N Jane E

AU - Malec, B A Mary

AU - Levin, Victor A

AU - Gutin, Phillip H

AU - Phillips, Theodore L

AU - Wilson, Charles B

N1 - This therapy was no more effective in patients with GBM than other reported series. In patients with malignant gliomas other than GBM, prolonged progression-free and overall survival is noted, without a median survival reached at the time of this report. In this subset of AG patients, survival is co ...

PY - 1998/1/1

Y1 - 1998/1/1

UR - https://www.ncbi.nlm.nih.gov/pubmed/9422558

U2 - 10.1016/S0360-3016(97)00566-X

DO - 10.1016/S0360-3016(97)00566-X

M3 - Article

VL - 40

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

ER -

Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors.

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