@article{231959483ebf4ce78c5188eefb8cb4e4,
title = "Phase II trial of ritonavir/lopinavir in patients with progressive or recurrent high-grade gliomas",
author = "Manmeet Ahluwalia and Carol Patton and Glen Stevens and Tanya Tekautz and Lilyana Angelov and Michael Vogelbaum and Weil, \{Robert J.\} and Chao, \{Samuel T.\} and Paul Elson and Suh, \{John H.\} and Gene Barnett and Peereboom, \{David Marc\}",
note = "Current therapies for recurrent or progressive high-grade gliomas (HGG, WHO grade 3-4) produce a 6-month progression-free survival of only 10-25\%. Migration and invasion by HGG is mediated in part by matrix metalloproteases (MMPs) which promote remodeling of the extracellular matrix. Several HIV protease inhibitors (HIVPI) decrease the expression of MMPs in astrocytes and microglia.",
year = "2011",
month = apr,
day = "1",
doi = "10.1007/S11060-010-0325-3",
language = "American English",
volume = "102",
journal = "Journal of neuro-oncology",
}