Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131.

TY - JOUR

T1 - Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131.

AU - Vogelbaum, Michael A.

AU - Hu, Chen

AU - Peereboom, David M.

AU - Macdonald, David R.

AU - Giannini, Caterina

AU - Suh, John H.

AU - Jenkins, Robert B.

AU - Laack, Nadia N.

AU - Brachman, David G.

AU - Shrieve, Dennis C.

AU - Souhami, Luis

AU - Mehta, Minesh P.

N1 - We report on the long-term results of a phase II study of pre-irradiation temozolomide followed by concurrent temozolomide and radiotherapy (RT) in patients with newly diagnosed anaplastic oligodendroglioma (AO) and mixed anaplastic oligoastrocytoma. Pre-RT temozolomide was given for up to 6 cycles. RT with concurrent temozolomide was administered to patients with less than a complete radiographic response.

PY - 2015/9/1

Y1 - 2015/9/1

UR - https://link.springer.com/content/pdf/10.1007%2Fs11060-015-1845-7.pdf

U2 - 10.1007/s11060-015-1845-7

DO - 10.1007/s11060-015-1845-7

M3 - Article

VL - 124

JO - Journal of neuro-oncology

JF - Journal of neuro-oncology

ER -