Phase II trial of patupilone in patients with brain metastases from breast cancer

David M. Peereboom; David M. Peereboom; Conleth Murphy; Manmeet S. Ahluwalia; Manmeet S. Ahluwalia; Alison Conlin; April Eichler; April Eichler; Catherine Van Poznak; Joseph Baar; Paul Elson; Andrew D. Seidman

doi:10.1093/NEUONC/NOT305

Phase II trial of patupilone in patients with brain metastases from breast cancer

David M. Peereboom, David M. Peereboom, Conleth Murphy, Manmeet S. Ahluwalia, Manmeet S. Ahluwalia, Alison Conlin, April Eichler, April Eichler, Catherine Van Poznak, Joseph Baar, Paul Elson, Andrew D. Seidman

Miami Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Neuro-oncology
Volume	16
DOIs	https://doi.org/10.1093/NEUONC/NOT305
State	Published - Apr 1 2014

Disciplines

Medicine and Health Sciences
Oncology
Surgery
Internal Medicine

Access to Document

10.1093/NEUONC/NOT305License: Unspecified

Cite this

@article{4b8e4130155f4f52b150701c034ed759,

title = "Phase II trial of patupilone in patients with brain metastases from breast cancer",

author = "Peereboom, \{David M.\} and Peereboom, \{David M.\} and Conleth Murphy and Ahluwalia, \{Manmeet S.\} and Ahluwalia, \{Manmeet S.\} and Alison Conlin and April Eichler and April Eichler and \{Van Poznak\}, Catherine and Joseph Baar and Paul Elson and Seidman, \{Andrew D.\}",

note = "Background For patients with progressive breast cancer brain metastasis (BCBM) after whole brain radiotherapy (WBRT), few options exist. Patupilone is an epothilone that crosses the blood-brain barrier. We hypothesized that patupilone would produce a 35\% 3-month CNS progression-free survival in women with BCBM after WBRT. Methods This multicenter phase II trial included 2 cohorts.",

year = "2014",

month = apr,

day = "1",

doi = "10.1093/NEUONC/NOT305",

language = "American English",

volume = "16",

journal = "Neuro-oncology",

}

TY - JOUR

T1 - Phase II trial of patupilone in patients with brain metastases from breast cancer

AU - Peereboom, David M.

AU - Murphy, Conleth

AU - Ahluwalia, Manmeet S.

AU - Conlin, Alison

AU - Eichler, April

AU - Van Poznak, Catherine

AU - Baar, Joseph

AU - Elson, Paul

AU - Seidman, Andrew D.

N1 - Background For patients with progressive breast cancer brain metastasis (BCBM) after whole brain radiotherapy (WBRT), few options exist. Patupilone is an epothilone that crosses the blood-brain barrier. We hypothesized that patupilone would produce a 35% 3-month CNS progression-free survival in women with BCBM after WBRT. Methods This multicenter phase II trial included 2 cohorts.

PY - 2014/4/1

Y1 - 2014/4/1

UR - http://europepmc.org/articles/PMC3956359

U2 - 10.1093/NEUONC/NOT305

DO - 10.1093/NEUONC/NOT305

M3 - Article

VL - 16

JO - Neuro-oncology

JF - Neuro-oncology

ER -

Phase II trial of patupilone in patients with brain metastases from breast cancer

Disciplines

Access to Document

Other files and links

Cite this