Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Michael D. Prados; Susan M. Chang; Nicholas Butowski; Rebecca DeBoer; Rupa Parvataneni; Hannah Carliner; Paul Kabuubi; Jennifer Ayers-Ringler; Jane Rabbitt; Margaretta Page; Anne Fedoroff; Penny K. Sneed; Mitchel S. Berger; Michael W. McDermott; Andrew T. Parsa; Scott Vandenberg; C. David James; Kathleen R. Lamborn; David Stokoe; Daphne A. Haas-Kogan

doi:10.1200/JCO.2008.18.9639

Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Michael D. Prados, Susan M. Chang, Nicholas Butowski, Rebecca DeBoer, Rupa Parvataneni, Hannah Carliner, Paul Kabuubi, Jennifer Ayers-Ringler, Jane Rabbitt, Margaretta Page, Anne Fedoroff, Penny K. Sneed, Mitchel S. Berger, Michael W. McDermott, Andrew T. Parsa, Scott Vandenberg, C. David James, Kathleen R. Lamborn, David Stokoe, Daphne A. Haas-Kogan

Miami Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Clinical Oncology
Volume	27
DOIs	https://doi.org/10.1200/JCO.2008.18.9639
State	Published - Feb 1 2009

Disciplines

Medicine and Health Sciences
Surgery
Oncology
Internal Medicine

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Prados, M. D., Chang, S. M., Butowski, N., DeBoer, R., Parvataneni, R., Carliner, H., Kabuubi, P., Ayers-Ringler, J., Rabbitt, J., Page, M., Fedoroff, A., Sneed, P. K., Berger, M. S., McDermott, M. W., Parsa, A. T., Vandenberg, S., James, C. D., Lamborn, K. R., Stokoe, D., & Haas-Kogan, D. A. (2009). Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma. Journal of Clinical Oncology, 27. https://doi.org/10.1200/JCO.2008.18.9639

Prados, MD, Chang, SM, Butowski, N, DeBoer, R, Parvataneni, R, Carliner, H, Kabuubi, P, Ayers-Ringler, J, Rabbitt, J, Page, M, Fedoroff, A, Sneed, PK, Berger, MS, McDermott, MW, Parsa, AT, Vandenberg, S, James, CD, Lamborn, KR, Stokoe, D & Haas-Kogan, DA 2009, 'Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma', Journal of Clinical Oncology, vol. 27. https://doi.org/10.1200/JCO.2008.18.9639

@article{2922ea5b19c24ceda46426e163be1229,

title = "Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma",

author = "Prados, \{Michael D.\} and Chang, \{Susan M.\} and Nicholas Butowski and Rebecca DeBoer and Rupa Parvataneni and Hannah Carliner and Paul Kabuubi and Jennifer Ayers-Ringler and Jane Rabbitt and Margaretta Page and Anne Fedoroff and Sneed, \{Penny K.\} and Berger, \{Mitchel S.\} and McDermott, \{Michael W.\} and Parsa, \{Andrew T.\} and Scott Vandenberg and James, \{C. David\} and Lamborn, \{Kathleen R.\} and David Stokoe and Haas-Kogan, \{Daphne A.\}",

note = "Purpose This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma. The objectives were to determine efficacy of this treatment as measured by survival and to explore the relationship between molecular markers and treatment response.",

year = "2009",

month = feb,

day = "1",

doi = "10.1200/JCO.2008.18.9639",

language = "American English",

volume = "27",

journal = "Journal of Clinical Oncology",

}

TY - JOUR

T1 - Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

AU - Prados, Michael D.

AU - Chang, Susan M.

AU - Butowski, Nicholas

AU - DeBoer, Rebecca

AU - Parvataneni, Rupa

AU - Carliner, Hannah

AU - Kabuubi, Paul

AU - Ayers-Ringler, Jennifer

AU - Rabbitt, Jane

AU - Page, Margaretta

AU - Fedoroff, Anne

AU - Sneed, Penny K.

AU - Berger, Mitchel S.

AU - McDermott, Michael W.

AU - Parsa, Andrew T.

AU - Vandenberg, Scott

AU - James, C. David

AU - Lamborn, Kathleen R.

AU - Stokoe, David

AU - Haas-Kogan, Daphne A.

N1 - Purpose This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma. The objectives were to determine efficacy of this treatment as measured by survival and to explore the relationship between molecular markers and treatment response.

PY - 2009/2/1

Y1 - 2009/2/1

UR - https://ascopubs.org/doi/pdf/10.1200/JCO.2008.18.9639

U2 - 10.1200/JCO.2008.18.9639

DO - 10.1200/JCO.2008.18.9639

M3 - Article

VL - 27

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

ER -

Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

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