Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme

Allen M. Chen; Susan Chang; Jean Pouliot; Penny K. Sneed; Michael D. Prados; Kathleen R. Lamborn; Mary K. Malec; Michael W. McDermott; Mitchell S. Berger; David A. Larson

doi:10.1016/J.IJROBP.2007.03.061

Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme

Allen M. Chen, Susan Chang, Jean Pouliot, Penny K. Sneed, Michael D. Prados, Kathleen R. Lamborn, Mary K. Malec, Michael W. McDermott, Mitchell S. Berger, David A. Larson

Miami Neuroscience Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	International Journal of Radiation Oncology Biology Physics
Volume	69
DOIs	https://doi.org/10.1016/J.IJROBP.2007.03.061
State	Published - Nov 1 2007

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Chen, A. M., Chang, S., Pouliot, J., Sneed, P. K., Prados, M. D., Lamborn, K. R., Malec, M. K., McDermott, M. W., Berger, M. S., & Larson, D. A. (2007). Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme. International Journal of Radiation Oncology Biology Physics, 69. https://doi.org/10.1016/J.IJROBP.2007.03.061

Chen, AM, Chang, S, Pouliot, J, Sneed, PK, Prados, MD, Lamborn, KR, Malec, MK, McDermott, MW, Berger, MS & Larson, DA 2007, 'Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme', International Journal of Radiation Oncology Biology Physics, vol. 69. https://doi.org/10.1016/J.IJROBP.2007.03.061

@article{c5cf49125ac147a8af42a384fdae691e,

title = "Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme",

author = "Chen, \{Allen M.\} and Susan Chang and Jean Pouliot and Sneed, \{Penny K.\} and Prados, \{Michael D.\} and Lamborn, \{Kathleen R.\} and Malec, \{Mary K.\} and McDermott, \{Michael W.\} and Berger, \{Mitchell S.\} and Larson, \{David A.\}",

note = "Purpose: To evaluate the feasibility of gross total resection and permanent I-125 brachytherapy followed by hyperfractionated radiotherapy for patients with newly diagnosed glioblastoma. Methods and materials: From April 1999 to May 2002, 21 patients with glioblastoma multiforme were enrolled on a Phase I protocol investigating planned gross total resection and immediate placement of permanent I-125 seeds, followed by postoperative hyperfractionated radiotherapy to a dose of 60 Gy at 100 cGy b.i.d., 5 days per week.",

year = "2007",

month = nov,

day = "1",

doi = "10.1016/J.IJROBP.2007.03.061",

language = "American English",

volume = "69",

journal = "International Journal of Radiation Oncology Biology Physics",

}

TY - JOUR

T1 - Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme

AU - Chen, Allen M.

AU - Chang, Susan

AU - Pouliot, Jean

AU - Sneed, Penny K.

AU - Prados, Michael D.

AU - Lamborn, Kathleen R.

AU - Malec, Mary K.

AU - McDermott, Michael W.

AU - Berger, Mitchell S.

AU - Larson, David A.

N1 - Purpose: To evaluate the feasibility of gross total resection and permanent I-125 brachytherapy followed by hyperfractionated radiotherapy for patients with newly diagnosed glioblastoma. Methods and materials: From April 1999 to May 2002, 21 patients with glioblastoma multiforme were enrolled on a Phase I protocol investigating planned gross total resection and immediate placement of permanent I-125 seeds, followed by postoperative hyperfractionated radiotherapy to a dose of 60 Gy at 100 cGy b.i.d., 5 days per week.

PY - 2007/11/1

Y1 - 2007/11/1

UR - http://www.ncbi.nlm.nih.gov/pubmed/17512132

U2 - 10.1016/J.IJROBP.2007.03.061

DO - 10.1016/J.IJROBP.2007.03.061

M3 - Article

VL - 69

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

ER -

Phase I Trial of Gross Total Resection, Permanent Iodine-125 Brachytherapy, and Hyperfractionated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme

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