MRI-Guided Adaptive Radiation Therapy

Cecil M Benitez; Michael D Chuong; Luise A Künzel; Daniela Thorwarth

doi:10.1016/j.semradonc.2023.10.013

MRI-Guided Adaptive Radiation Therapy

Cecil M Benitez, Michael D Chuong, Luise A Künzel, Daniela Thorwarth

Miami Cancer Institute

Research output: Contribution to journal › Review article › peer-review

Abstract

Magnetic resonance imaging-guided radiation therapy (MRIgRT) has improved soft tissue contrast over computed tomography (CT) based image-guided RT. Superior visualization of the target and surrounding radiosensitive structures has the potential to improve oncological outcomes partly due to safer dose-escalation and adaptive planning. In this review, we highlight the workflow of adaptive MRIgRT planning, which includes simulation imaging, daily MRI, identifying isocenter shifts, contouring, plan optimization, quality control, and delivery. Increased utilization of MRIgRT will depend on addressing technical limitations of this technology, while addressing treatment efficacy, cost-effectiveness, and workflow training.

Original language	English
Pages (from-to)	84-91
Number of pages	8
Journal	Seminars in radiation oncology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1016/j.semradonc.2023.10.013
State	Published - Dec 2024

Keywords

Humans
Radiotherapy Planning, Computer-Assisted/methods
Tomography, X-Ray Computed
Magnetic Resonance Imaging/methods
Radiotherapy, Image-Guided/methods

Access to Document

10.1016/j.semradonc.2023.10.013

Cite this

@article{65b97084186f41f9862a33a5d044945f,

title = "MRI-Guided Adaptive Radiation Therapy",

abstract = "Magnetic resonance imaging-guided radiation therapy (MRIgRT) has improved soft tissue contrast over computed tomography (CT) based image-guided RT. Superior visualization of the target and surrounding radiosensitive structures has the potential to improve oncological outcomes partly due to safer dose-escalation and adaptive planning. In this review, we highlight the workflow of adaptive MRIgRT planning, which includes simulation imaging, daily MRI, identifying isocenter shifts, contouring, plan optimization, quality control, and delivery. Increased utilization of MRIgRT will depend on addressing technical limitations of this technology, while addressing treatment efficacy, cost-effectiveness, and workflow training.",

keywords = "Humans, Radiotherapy Planning, Computer-Assisted/methods, Tomography, X-Ray Computed, Magnetic Resonance Imaging/methods, Radiotherapy, Image-Guided/methods",

author = "Benitez, {Cecil M} and Chuong, {Michael D} and K{\"u}nzel, {Luise A} and Daniela Thorwarth",

year = "2024",

month = dec,

doi = "10.1016/j.semradonc.2023.10.013",

language = "English",

volume = "34",

pages = "84--91",

journal = "Seminars in radiation oncology",

issn = "1053-4296",

number = "1",

}

TY - JOUR

T1 - MRI-Guided Adaptive Radiation Therapy

AU - Benitez, Cecil M

AU - Chuong, Michael D

AU - Künzel, Luise A

AU - Thorwarth, Daniela

PY - 2024/12

Y1 - 2024/12

N2 - Magnetic resonance imaging-guided radiation therapy (MRIgRT) has improved soft tissue contrast over computed tomography (CT) based image-guided RT. Superior visualization of the target and surrounding radiosensitive structures has the potential to improve oncological outcomes partly due to safer dose-escalation and adaptive planning. In this review, we highlight the workflow of adaptive MRIgRT planning, which includes simulation imaging, daily MRI, identifying isocenter shifts, contouring, plan optimization, quality control, and delivery. Increased utilization of MRIgRT will depend on addressing technical limitations of this technology, while addressing treatment efficacy, cost-effectiveness, and workflow training.

AB - Magnetic resonance imaging-guided radiation therapy (MRIgRT) has improved soft tissue contrast over computed tomography (CT) based image-guided RT. Superior visualization of the target and surrounding radiosensitive structures has the potential to improve oncological outcomes partly due to safer dose-escalation and adaptive planning. In this review, we highlight the workflow of adaptive MRIgRT planning, which includes simulation imaging, daily MRI, identifying isocenter shifts, contouring, plan optimization, quality control, and delivery. Increased utilization of MRIgRT will depend on addressing technical limitations of this technology, while addressing treatment efficacy, cost-effectiveness, and workflow training.

KW - Humans

KW - Radiotherapy Planning, Computer-Assisted/methods

KW - Tomography, X-Ray Computed

KW - Magnetic Resonance Imaging/methods

KW - Radiotherapy, Image-Guided/methods

U2 - 10.1016/j.semradonc.2023.10.013

DO - 10.1016/j.semradonc.2023.10.013

M3 - Review article

C2 - 38105097

SN - 1053-4296

VL - 34

SP - 84

EP - 91

JO - Seminars in radiation oncology

JF - Seminars in radiation oncology

IS - 1

ER -