Intratumoral Activity of ONC201 in Adult Recurrent Glioblastoma Patients

Yazmin Odia

Intratumoral Activity of ONC201 in Adult Recurrent Glioblastoma Patients

Yazmin Odia

Miami Cancer Institute

Research output: Contribution to conference › Presentation

Original language	American English
State	Published - 2018
Event	ASCO 2018 - Chicago, IL Duration: Jan 1 2018 → …

Conference

Conference	ASCO 2018
Period	1/1/18 → …

Disciplines

Medicine and Health Sciences
Neoplasms
Neurology
Oncology

Cite this

@conference{ade4c2cde48e426ab802cd4114990c7a,

title = "Intratumoral Activity of ONC201 in Adult Recurrent Glioblastoma Patients",

author = "Yazmin Odia",

note = "e14034 Background: ONC201 is an antagonist of the G protein-coupled receptor DRD2 that crosses the blood-brain barrier and induces tumor cell apoptosis in preclinical models. The anti-tumor activity of ONC201 is pronounced in cells with low DRD5 expression and is associated with induction of the ATF4/CHOP/DR5-mediated integrated stress response pathway to trigger apoptosis.; ASCO 2018 ; Conference date: 01-01-2018",

year = "2018",

language = "American English",

}

TY - CONF

T1 - Intratumoral Activity of ONC201 in Adult Recurrent Glioblastoma Patients

AU - Odia, Yazmin

N1 - e14034 Background: ONC201 is an antagonist of the G protein-coupled receptor DRD2 that crosses the blood-brain barrier and induces tumor cell apoptosis in preclinical models. The anti-tumor activity of ONC201 is pronounced in cells with low DRD5 expression and is associated with induction of the ATF4/CHOP/DR5-mediated integrated stress response pathway to trigger apoptosis.

PY - 2018

Y1 - 2018

UR - https://ascopubs.org/doi/abs/10.1200/JCO.2018.36.15_suppl.e14034

M3 - Presentation

T2 - ASCO 2018

Y2 - 1 January 2018

ER -

Intratumoral Activity of ONC201 in Adult Recurrent Glioblastoma Patients

Conference

Disciplines

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Cite this