@article{822cdf0abadf41d090e07fa1462b2441,
title = "Intratumoral activity of ONC201 in adult recurrent glioblastoma patients.",
author = "Isabel Arrillaga and Yazmin Odia and Allen, \{Joshua E.\} and Prabhu, \{Varun V.\} and Rohinton Tarapore and Wolfgang Oster and Mehta, \{Minesh P.\} and Wen, \{Patrick Y.\} and Tracy Batchelor",
note = "e14034 Background: ONC201 is an antagonist of the G protein-coupled receptor DRD2 that crosses the blood-brain barrier and induces tumor cell apoptosis in preclinical models. The anti-tumor activity of ONC201 is pronounced in cells with low DRD5 expression and is associated with induction of the ATF4/CHOP/DR5-mediated integrated stress response pathway to trigger apoptosis.",
year = "2018",
month = may,
day = "20",
doi = "10.1200/JCO.2018.36.15\_suppl.e14034",
language = "American English",
volume = "36",
journal = "Journal of Clinical Oncology",
}