Intermonomer Hydrogen Bonds Enhance GxxxG-driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix-helix Association in Membranes

Charles Lawrie; E.S. Sulistijo; K.R. MacKenzie

Intermonomer Hydrogen Bonds Enhance GxxxG-driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix-helix Association in Membranes

Charles Lawrie
, E.S. Sulistijo
, K.R. MacKenzie

Baptist Health Orthopedic Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Molecular Biology
Volume	396
State	Published - Mar 2010

Disciplines

Medicine and Health Sciences

Cite this

@article{8d8b85dc24fd4043b6c9431febc498d2,

title = "Intermonomer Hydrogen Bonds Enhance GxxxG-driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix-helix Association in Membranes",

author = "Charles Lawrie and E.S. Sulistijo and K.R. MacKenzie",

note = "We determined the sequence dependence of human BNIP3 transmembrane domain dimerization using the biological assay TOXCAT. Mutants in which intermonomer hydrogen bonds between Ser172 and His173 are abolished show moderate interaction, indicating that side-chain hydrogen bonds contribute to dimer stab ...",

year = "2010",

month = mar,

language = "American English",

volume = "396",

journal = "Journal of Molecular Biology",

}

TY - JOUR

T1 - Intermonomer Hydrogen Bonds Enhance GxxxG-driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix-helix Association in Membranes

AU - Lawrie, Charles

AU - Sulistijo, E.S.

AU - MacKenzie, K.R.

N1 - We determined the sequence dependence of human BNIP3 transmembrane domain dimerization using the biological assay TOXCAT. Mutants in which intermonomer hydrogen bonds between Ser172 and His173 are abolished show moderate interaction, indicating that side-chain hydrogen bonds contribute to dimer stab ...

PY - 2010/3

Y1 - 2010/3

UR - https://pubmed.ncbi.nlm.nih.gov/20026130/

M3 - Article

VL - 396

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

ER -

Intermonomer Hydrogen Bonds Enhance GxxxG-driven Dimerization of the BNIP3 Transmembrane Domain: Roles for Sequence Context in Helix-helix Association in Membranes

Disciplines

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