Integrating Comprehensive Genomic Profiling with Treatment Decisions – Experience Gained while Treating 139 Advanced Breast Carcinomas

TY - JOUR

T1 - Integrating Comprehensive Genomic Profiling with Treatment Decisions – Experience Gained while Treating 139 Advanced Breast Carcinomas

AU - Mahtani, Reshma

AU - Gay, L.

AU - Chung, J.

AU - Hartmaier, R.

AU - Sokol, E.

AU - Elvin, J.A.

AU - Daniel, S.

N1 - Abstract. Background: Comprehensive Genomic Profiling (CGP) using next-generation sequencing (NGS) technology can provide insight into potentially clinically relevant genomic alterations (CRGA) within a patient's breast cancer. For example, HER2 amplification status and targetable short variants (SV), acquired ESR1 or BRCA1/2 resistance mutations, and the presence of targetable alterations in the PI3K kinase.

PY - 2018/2/15

Y1 - 2018/2/15

UR - https://aacrjournals.org/cancerres/article/78/4_Supplement/P5-21-20/632861/Abstract-P5-21-20-Integrating-comprehensive

M3 - Article

VL - 78

JO - Cancer Research / San Antonio Breast Cancer Symposium 2017

JF - Cancer Research / San Antonio Breast Cancer Symposium 2017

ER -