Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis

Tyler J Alban; Alvaro G Alvarado; Mia D Sorensen; Mia D Sorensen; Defne Bayik; Josephine Volovetz; Emily Serbinowski; Erin E Mulkearns-Hubert; Maksim Sinyuk; James S Hale; Giovana R Onzi; Giovana R Onzi; Mary McGraw; Pengjing Huang; Matthew M Grabowski; Matthew M Grabowski; Connor A Wathen; Manmeet S Ahluwalia; Tomas Radivoyevitch; Harley I Kornblum; Bjarne W Kristensen; Bjarne W Kristensen; Michael A Vogelbaum; Justin D Lathia; Justin D Lathia

doi:10.1172/JCI.INSIGHT.122264

Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis

Tyler J Alban, Alvaro G Alvarado, Mia D Sorensen, Mia D Sorensen, Defne Bayik, Josephine Volovetz, Emily Serbinowski, Erin E Mulkearns-Hubert, Maksim Sinyuk, James S Hale, Giovana R Onzi, Giovana R Onzi, Mary McGraw, Pengjing Huang, Matthew M Grabowski, Matthew M Grabowski, Connor A Wathen, Manmeet S Ahluwalia, Tomas Radivoyevitch, Harley I KornblumBjarne W Kristensen, Bjarne W Kristensen, Michael A Vogelbaum, Justin D Lathia, Justin D Lathia

Miami Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	JCI insight
Volume	3
DOIs	https://doi.org/10.1172/JCI.INSIGHT.122264
State	Published - Nov 7 2018

Disciplines

Medicine and Health Sciences
Oncology

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Alban, T. J., Alvarado, A. G., Sorensen, M. D., Sorensen, M. D., Bayik, D., Volovetz, J., Serbinowski, E., Mulkearns-Hubert, E. E., Sinyuk, M., Hale, J. S., Onzi, G. R., Onzi, G. R., McGraw, M., Huang, P., Grabowski, M. M., Grabowski, M. M., Wathen, C. A., Ahluwalia, M. S., Radivoyevitch, T., ... Lathia, J. D. (2018). Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis. JCI insight, 3. https://doi.org/10.1172/JCI.INSIGHT.122264

Alban, TJ, Alvarado, AG, Sorensen, MD, Sorensen, MD, Bayik, D, Volovetz, J, Serbinowski, E, Mulkearns-Hubert, EE, Sinyuk, M, Hale, JS, Onzi, GR, Onzi, GR, McGraw, M, Huang, P, Grabowski, MM, Grabowski, MM, Wathen, CA, Ahluwalia, MS, Radivoyevitch, T, Kornblum, HI, Kristensen, BW, Kristensen, BW, Vogelbaum, MA, Lathia, JD & Lathia, JD 2018, 'Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis', JCI insight, vol. 3. https://doi.org/10.1172/JCI.INSIGHT.122264

@article{60118760e37f4e609d051196133f5e14,

title = "Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis",

author = "Alban, {Tyler J} and Alvarado, {Alvaro G} and Sorensen, {Mia D} and Sorensen, {Mia D} and Defne Bayik and Josephine Volovetz and Emily Serbinowski and Mulkearns-Hubert, {Erin E} and Maksim Sinyuk and Hale, {James S} and Onzi, {Giovana R} and Onzi, {Giovana R} and Mary McGraw and Pengjing Huang and Grabowski, {Matthew M} and Grabowski, {Matthew M} and Wathen, {Connor A} and Ahluwalia, {Manmeet S} and Tomas Radivoyevitch and Kornblum, {Harley I} and Kristensen, {Bjarne W} and Kristensen, {Bjarne W} and Vogelbaum, {Michael A} and Lathia, {Justin D} and Lathia, {Justin D}",

note = "Glioblastoma (GBM) remains uniformly lethal, and despite a large accumulation of immune cells in the microenvironment, there is limited antitumor immune response. To overcome these challenges, a comprehensive understanding of GBM systemic immune response during disease progression is required.",

year = "2018",

month = nov,

day = "7",

doi = "10.1172/JCI.INSIGHT.122264",

language = "American English",

volume = "3",

journal = "JCI insight",

}

TY - JOUR

T1 - Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis

AU - Alban, Tyler J

AU - Alvarado, Alvaro G

AU - Sorensen, Mia D

AU - Bayik, Defne

AU - Volovetz, Josephine

AU - Serbinowski, Emily

AU - Mulkearns-Hubert, Erin E

AU - Sinyuk, Maksim

AU - Hale, James S

AU - Onzi, Giovana R

AU - McGraw, Mary

AU - Huang, Pengjing

AU - Grabowski, Matthew M

AU - Wathen, Connor A

AU - Ahluwalia, Manmeet S

AU - Radivoyevitch, Tomas

AU - Kornblum, Harley I

AU - Kristensen, Bjarne W

AU - Vogelbaum, Michael A

AU - Lathia, Justin D

N1 - Glioblastoma (GBM) remains uniformly lethal, and despite a large accumulation of immune cells in the microenvironment, there is limited antitumor immune response. To overcome these challenges, a comprehensive understanding of GBM systemic immune response during disease progression is required.

PY - 2018/11/7

Y1 - 2018/11/7

UR - https://insight.jci.org/articles/view/122264/sd/1

U2 - 10.1172/JCI.INSIGHT.122264

DO - 10.1172/JCI.INSIGHT.122264

M3 - Article

VL - 3

JO - JCI insight

JF - JCI insight

ER -

Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis

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