CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION

Patrick Wen; Lorenzo Trippa; Eudocia Lee; Geoffrey Fell; Rifaquat Rahman; Isabel Arrillaga-Romany; Mehdi Touat; Christine McCluskey; Jennifer Brunno; Sarah Gaffey; Jan Drappatz; Andrew Lassman; Evanthia Galanis; Manmeet Ahluwalia; Howard Colman; Louis Nabors; Jaroslaw Hepel; Heinrich Elinzano; David Schiff; Ugonma Chukwueke; Rameen Beroukhim; Lakshmi Nayak; Jose Mcfaline-Figueroa; Tracy Batchelor; Mikael Rinne; Thomas Kaley; Christine Lu-Emerson; Wenya Linda Bi; Omar Arnaout; Pier-Paolo Peruzzi; Lisa Doherty; Daphne Haas-Kogan; Shyam Tanguturi; Daniel Cagney; Ayal A Aizer; Mary Welch; Maria Lavallee; Brittany Fisher-Longden; Shanna Dowling; Jack Geduldig; Sandro Santagata; David Meredith; E Antonio Chiocca; David Reardon; Keith Ligon; Brian Alexander

doi:10.1093/NEUONC/NOAA215.179

CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION

Patrick Wen
, Lorenzo Trippa
, Eudocia Lee
, Geoffrey Fell
, Rifaquat Rahman
, Isabel Arrillaga-Romany
, Mehdi Touat
, Christine McCluskey
, Jennifer Brunno
, Sarah Gaffey
, Jan Drappatz
, Andrew Lassman
, Evanthia Galanis
, Manmeet Ahluwalia
, Howard Colman
, Louis Nabors
, Jaroslaw Hepel
, Heinrich Elinzano
, David Schiff
, Ugonma Chukwueke

Rameen Beroukhim, Lakshmi Nayak, Jose Mcfaline-Figueroa, Tracy Batchelor, Mikael Rinne, Thomas Kaley, Christine Lu-Emerson, Wenya Linda Bi, Omar Arnaout, Pier-Paolo Peruzzi, Lisa Doherty, Daphne Haas-Kogan, Shyam Tanguturi, Daniel Cagney, Ayal A Aizer, Mary Welch, Maria Lavallee, Brittany Fisher-Longden, Shanna Dowling, Jack Geduldig, Sandro Santagata, David Meredith, E Antonio Chiocca, David Reardon, Keith Ligon, Brian Alexander

Miami Cancer Institute

Research output: Contribution to conference › Presentation

Original language	American English
DOIs	https://doi.org/10.1093/NEUONC/NOAA215.179
State	Published - Nov 9 2020
Event	Neuro-oncology - Duration: Nov 9 2020 → …

Conference

Conference	Neuro-oncology
Period	11/9/20 → …

Disciplines

Medicine and Health Sciences
Oncology
Internal Medicine

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10.1093/NEUONC/NOAA215.179License: Unspecified

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Wen, P., Trippa, L., Lee, E., Fell, G., Rahman, R., Arrillaga-Romany, I., Touat, M., McCluskey, C., Brunno, J., Gaffey, S., Drappatz, J., Lassman, A., Galanis, E., Ahluwalia, M., Colman, H., Nabors, L., Hepel, J., Elinzano, H., Schiff, D., ... Alexander, B. (2020). CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION. Neuro-oncology. https://doi.org/10.1093/NEUONC/NOAA215.179

Wen, P, Trippa, L, Lee, E, Fell, G, Rahman, R, Arrillaga-Romany, I, Touat, M, McCluskey, C, Brunno, J, Gaffey, S, Drappatz, J, Lassman, A, Galanis, E, Ahluwalia, M, Colman, H, Nabors, L, Hepel, J, Elinzano, H, Schiff, D, Chukwueke, U, Beroukhim, R, Nayak, L, Mcfaline-Figueroa, J, Batchelor, T, Rinne, M, Kaley, T, Lu-Emerson, C, Bi, WL, Arnaout, O, Peruzzi, P-P, Doherty, L, Haas-Kogan, D, Tanguturi, S, Cagney, D, Aizer, AA, Welch, M, Lavallee, M, Fisher-Longden, B, Dowling, S, Geduldig, J, Santagata, S, Meredith, D, Chiocca, EA, Reardon, D, Ligon, K & Alexander, B 2020, 'CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION', Neuro-oncology, 11/9/20. https://doi.org/10.1093/NEUONC/NOAA215.179

@conference{21fd8eb857e44c2fa4fcfd8a6408e701,

title = "CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION",

author = "Patrick Wen and Lorenzo Trippa and Eudocia Lee and Geoffrey Fell and Rifaquat Rahman and Isabel Arrillaga-Romany and Mehdi Touat and Christine McCluskey and Jennifer Brunno and Sarah Gaffey and Jan Drappatz and Andrew Lassman and Evanthia Galanis and Manmeet Ahluwalia and Howard Colman and Louis Nabors and Jaroslaw Hepel and Heinrich Elinzano and David Schiff and Ugonma Chukwueke and Rameen Beroukhim and Lakshmi Nayak and Jose Mcfaline-Figueroa and Tracy Batchelor and Mikael Rinne and Thomas Kaley and Christine Lu-Emerson and Bi, \{Wenya Linda\} and Omar Arnaout and Pier-Paolo Peruzzi and Lisa Doherty and Daphne Haas-Kogan and Shyam Tanguturi and Daniel Cagney and Aizer, \{Ayal A\} and Mary Welch and Maria Lavallee and Brittany Fisher-Longden and Shanna Dowling and Jack Geduldig and Sandro Santagata and David Meredith and Chiocca, \{E Antonio\} and David Reardon and Keith Ligon and Brian Alexander",

note = "AbstractBACKGROUND. The cyclin D-CDK4/6-Rb pathway is activated in most glioblastomas. Abemaciclib is a potent CDK4/6 inhibitor with good brain penetration appr; Neuro-oncology ; Conference date: 09-11-2020",

year = "2020",

month = nov,

day = "9",

doi = "10.1093/NEUONC/NOAA215.179",

language = "American English",

}

TY - CONF

T1 - CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION

AU - Wen, Patrick

AU - Trippa, Lorenzo

AU - Lee, Eudocia

AU - Fell, Geoffrey

AU - Rahman, Rifaquat

AU - Arrillaga-Romany, Isabel

AU - Touat, Mehdi

AU - McCluskey, Christine

AU - Brunno, Jennifer

AU - Gaffey, Sarah

AU - Drappatz, Jan

AU - Lassman, Andrew

AU - Galanis, Evanthia

AU - Ahluwalia, Manmeet

AU - Colman, Howard

AU - Nabors, Louis

AU - Hepel, Jaroslaw

AU - Elinzano, Heinrich

AU - Schiff, David

AU - Chukwueke, Ugonma

AU - Beroukhim, Rameen

AU - Nayak, Lakshmi

AU - Mcfaline-Figueroa, Jose

AU - Batchelor, Tracy

AU - Rinne, Mikael

AU - Kaley, Thomas

AU - Lu-Emerson, Christine

AU - Bi, Wenya Linda

AU - Arnaout, Omar

AU - Peruzzi, Pier-Paolo

AU - Doherty, Lisa

AU - Haas-Kogan, Daphne

AU - Tanguturi, Shyam

AU - Cagney, Daniel

AU - Aizer, Ayal A

AU - Welch, Mary

AU - Lavallee, Maria

AU - Fisher-Longden, Brittany

AU - Dowling, Shanna

AU - Geduldig, Jack

AU - Santagata, Sandro

AU - Meredith, David

AU - Chiocca, E Antonio

AU - Reardon, David

AU - Ligon, Keith

AU - Alexander, Brian

N1 - AbstractBACKGROUND. The cyclin D-CDK4/6-Rb pathway is activated in most glioblastomas. Abemaciclib is a potent CDK4/6 inhibitor with good brain penetration appr

PY - 2020/11/9

Y1 - 2020/11/9

UR - http://academic.oup.com/neuro-oncology/article-pdf/22/Supplement_2/ii44/34689799/noaa215.179.pdf

U2 - 10.1093/NEUONC/NOAA215.179

DO - 10.1093/NEUONC/NOAA215.179

M3 - Presentation

T2 - Neuro-oncology

Y2 - 9 November 2020

ER -

CTNI-12. PRELIMINARY RESULTS OF THE ABEMACICLIB ARM IN THE INDIVIDUALIZED SCREENING TRIAL OF INNOVATIVE GLIOBLASTOMA THERAPY (INSIGHT): A PHASE II PLATFORM TRIAL USING BAYESIAN ADAPTIVE RANDOMIZATION

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