Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

David C. Whitcomb; Jessica LaRusch; Alyssa M. Krasinskas; Lambertus Klei; Jill P. Smith; Randall E. Brand; John P. Neoptolemos; Markus M. Lerch; Matt Tector; Bimaljit S. Sandhu; Nalini M. Guda; Lidiya Orlichenko; Samer Alkaade; Stephen T. Amann; Michelle A. Anderson; John Baillie; Peter A. Banks; Darwin Conwell; Gregory A. Coté; Peter B. Cotton; James DiSario; Lindsay A. Farrer; Chris E. Forsmark; Marianne Johnstone; Timothy B. Gardner; Andres Gelrud; William Greenhalf; Jonathan L. Haines; Douglas J. Hartman; Robert A. Hawes; Christopher Lawrence; Michele Lewis; Julia Mayerle; Richard Mayeux; Nadine M. Melhem; Mary E. Money; Thiruvengadam Muniraj; Georgios I. Papachristou; Margaret A. Pericak-Vance; Joseph Romagnuolo; Gerard D. Schellenberg; Stuart Sherman; Peter Simon; Vijay P. Singh; Adam Slivka; Donna Stolz; Robert Sutton; Frank Ulrich Weiss; C. Mel Wilcox

doi:10.1038/ng.2466

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

David C. Whitcomb, Jessica LaRusch, Alyssa M. Krasinskas, Lambertus Klei, Jill P. Smith, Randall E. Brand, John P. Neoptolemos, Markus M. Lerch, Matt Tector, Bimaljit S. Sandhu, Nalini M. Guda, Lidiya Orlichenko, Samer Alkaade, Stephen T. Amann, Michelle A. Anderson, John Baillie, Peter A. Banks, Darwin Conwell, Gregory A. Coté, Peter B. CottonJames DiSario, Lindsay A. Farrer, Chris E. Forsmark, Marianne Johnstone, Timothy B. Gardner, Andres Gelrud, William Greenhalf, Jonathan L. Haines, Douglas J. Hartman, Robert A. Hawes, Christopher Lawrence, Michele Lewis, Julia Mayerle, Richard Mayeux, Nadine M. Melhem, Mary E. Money, Thiruvengadam Muniraj, Georgios I. Papachristou, Margaret A. Pericak-Vance, Joseph Romagnuolo, Gerard D. Schellenberg, Stuart Sherman, Peter Simon, Vijay P. Singh, Adam Slivka, Donna Stolz, Robert Sutton, Frank Ulrich Weiss, C. Mel Wilcox

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Nature Genetics
Volume	44
DOIs	https://doi.org/10.1038/ng.2466
State	Published - Dec 1 2012
Externally published	Yes

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Biology
Genetics

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Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., ... Wilcox, C. M. (2012). Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nature Genetics, 44. https://doi.org/10.1038/ng.2466

Whitcomb, DC, LaRusch, J, Krasinskas, AM, Klei, L, Smith, JP, Brand, RE, Neoptolemos, JP, Lerch, MM, Tector, M, Sandhu, BS, Guda, NM, Orlichenko, L, Alkaade, S, Amann, ST, Anderson, MA, Baillie, J, Banks, PA, Conwell, D, Coté, GA, Cotton, PB, DiSario, J, Farrer, LA, Forsmark, CE, Johnstone, M, Gardner, TB, Gelrud, A, Greenhalf, W, Haines, JL, Hartman, DJ, Hawes, RA, Lawrence, C, Lewis, M, Mayerle, J, Mayeux, R, Melhem, NM, Money, ME, Muniraj, T, Papachristou, GI, Pericak-Vance, MA, Romagnuolo, J, Schellenberg, GD, Sherman, S, Simon, P, Singh, VP, Slivka, A, Stolz, D, Sutton, R, Weiss, FU & Wilcox, CM 2012, 'Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis', Nature Genetics, vol. 44. https://doi.org/10.1038/ng.2466

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title = "Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis",

author = "Whitcomb, \{David C.\} and Jessica LaRusch and Krasinskas, \{Alyssa M.\} and Lambertus Klei and Smith, \{Jill P.\} and Brand, \{Randall E.\} and Neoptolemos, \{John P.\} and Lerch, \{Markus M.\} and Matt Tector and Sandhu, \{Bimaljit S.\} and Guda, \{Nalini M.\} and Lidiya Orlichenko and Samer Alkaade and Amann, \{Stephen T.\} and Anderson, \{Michelle A.\} and John Baillie and Banks, \{Peter A.\} and Darwin Conwell and Cot{\'e}, \{Gregory A.\} and Cotton, \{Peter B.\} and James DiSario and Farrer, \{Lindsay A.\} and Forsmark, \{Chris E.\} and Marianne Johnstone and Gardner, \{Timothy B.\} and Andres Gelrud and William Greenhalf and Haines, \{Jonathan L.\} and Hartman, \{Douglas J.\} and Hawes, \{Robert A.\} and Christopher Lawrence and Michele Lewis and Julia Mayerle and Richard Mayeux and Melhem, \{Nadine M.\} and Money, \{Mary E.\} and Thiruvengadam Muniraj and Papachristou, \{Georgios I.\} and Pericak-Vance, \{Margaret A.\} and Joseph Romagnuolo and Schellenberg, \{Gerard D.\} and Stuart Sherman and Peter Simon and Singh, \{Vijay P.\} and Adam Slivka and Donna Stolz and Robert Sutton and Weiss, \{Frank Ulrich\} and Wilcox, \{C. Mel\}",

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day = "1",

doi = "10.1038/ng.2466",

language = "American English",

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T1 - Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

AU - Whitcomb, David C.

AU - LaRusch, Jessica

AU - Krasinskas, Alyssa M.

AU - Klei, Lambertus

AU - Smith, Jill P.

AU - Brand, Randall E.

AU - Neoptolemos, John P.

AU - Lerch, Markus M.

AU - Tector, Matt

AU - Sandhu, Bimaljit S.

AU - Guda, Nalini M.

AU - Orlichenko, Lidiya

AU - Alkaade, Samer

AU - Amann, Stephen T.

AU - Anderson, Michelle A.

AU - Baillie, John

AU - Banks, Peter A.

AU - Conwell, Darwin

AU - Coté, Gregory A.

AU - Cotton, Peter B.

AU - DiSario, James

AU - Farrer, Lindsay A.

AU - Forsmark, Chris E.

AU - Johnstone, Marianne

AU - Gardner, Timothy B.

AU - Gelrud, Andres

AU - Greenhalf, William

AU - Haines, Jonathan L.

AU - Hartman, Douglas J.

AU - Hawes, Robert A.

AU - Lawrence, Christopher

AU - Lewis, Michele

AU - Mayerle, Julia

AU - Mayeux, Richard

AU - Melhem, Nadine M.

AU - Money, Mary E.

AU - Muniraj, Thiruvengadam

AU - Papachristou, Georgios I.

AU - Pericak-Vance, Margaret A.

AU - Romagnuolo, Joseph

AU - Schellenberg, Gerard D.

AU - Sherman, Stuart

AU - Simon, Peter

AU - Singh, Vijay P.

AU - Slivka, Adam

AU - Stolz, Donna

AU - Sutton, Robert

AU - Weiss, Frank Ulrich

AU - Wilcox, C. Mel

PY - 2012/12/1

Y1 - 2012/12/1

UR - http://dash.harvard.edu/bitstream/handle/1/11708571/3510344.pdf?sequence=1

U2 - 10.1038/ng.2466

DO - 10.1038/ng.2466

M3 - Article

VL - 44

JO - Nature Genetics

JF - Nature Genetics

ER -

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

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