Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

Peter J. Mazzone; Peter B. Bach; Jacob Carey; Caitlin A. Schonewolf; Katalin Bognar; Manmeet S. Ahluwalia; Marcia Cruz-Correa; David Gierada; Sonali Kotagiri; Kathryn Lloyd; Fabien Maldonado; Jesse D. Ortendahl; Lecia V. Sequist; Gerard A. Silvestri; Nichole Tanner; Jeffrey C. Thompson; Anil Vachani; Kwok Kin Wong; Ali H. Zaidi; Joseph Catallini; Ariel Gershman; Keith Lumbard; Laurel K. Millberg; Jeff Nawrocki; Carter Portwood; Aakanksha Rangnekar; Carolina Campos Sheridan; Niti Trivedi; Tony Wu; Yuhua Zong; Lindsey Cotton; Allison Ryan; Christopher Cisar; Alessandro Leal; Nicholas Dracopoli; Robert B. Scharpf; Victor E. Velculescu; Luke R.G. Pike

doi:10.1158/2159-8290.CD-24-0519

Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

Peter J. Mazzone
, Peter B. Bach
, Jacob Carey
, Caitlin A. Schonewolf
, Katalin Bognar
, Manmeet S. Ahluwalia
, Marcia Cruz-Correa
, David Gierada
, Sonali Kotagiri
, Kathryn Lloyd
, Fabien Maldonado
, Jesse D. Ortendahl
, Lecia V. Sequist
, Gerard A. Silvestri
, Nichole Tanner
, Jeffrey C. Thompson
, Anil Vachani
, Kwok Kin Wong
, Ali H. Zaidi
, Joseph Catallini

Ariel Gershman, Keith Lumbard, Laurel K. Millberg, Jeff Nawrocki, Carter Portwood, Aakanksha Rangnekar, Carolina Campos Sheridan, Niti Trivedi, Tony Wu, Yuhua Zong, Lindsey Cotton, Allison Ryan, Christopher Cisar, Alessandro Leal, Nicholas Dracopoli, Robert B. Scharpf, Victor E. Velculescu, Luke R.G. Pike

Miami Cancer Institute

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2224-2242
Number of pages	19
Journal	Cancer Discovery
Volume	14
Issue number	11
DOIs	https://doi.org/10.1158/2159-8290.CD-24-0519
State	Published - Nov 1 2024

ASJC Scopus Subject Areas

Oncology

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10.1158/2159-8290.CD-24-0519

Cite this

Mazzone, P. J., Bach, P. B., Carey, J., Schonewolf, C. A., Bognar, K., Ahluwalia, M. S., Cruz-Correa, M., Gierada, D., Kotagiri, S., Lloyd, K., Maldonado, F., Ortendahl, J. D., Sequist, L. V., Silvestri, G. A., Tanner, N., Thompson, J. C., Vachani, A., Wong, K. K., Zaidi, A. H., ... Pike, L. R. G. (2024). Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection. Cancer Discovery, 14(11), 2224-2242. https://doi.org/10.1158/2159-8290.CD-24-0519

Mazzone, PJ, Bach, PB, Carey, J, Schonewolf, CA, Bognar, K, Ahluwalia, MS, Cruz-Correa, M, Gierada, D, Kotagiri, S, Lloyd, K, Maldonado, F, Ortendahl, JD, Sequist, LV, Silvestri, GA, Tanner, N, Thompson, JC, Vachani, A, Wong, KK, Zaidi, AH, Catallini, J, Gershman, A, Lumbard, K, Millberg, LK, Nawrocki, J, Portwood, C, Rangnekar, A, Sheridan, CC, Trivedi, N, Wu, T, Zong, Y, Cotton, L, Ryan, A, Cisar, C, Leal, A, Dracopoli, N, Scharpf, RB, Velculescu, VE & Pike, LRG 2024, 'Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection', Cancer Discovery, vol. 14, no. 11, pp. 2224-2242. https://doi.org/10.1158/2159-8290.CD-24-0519

@article{65dea4c7feb24f6b83a759fdeab5e7c0,

title = "Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection",

author = "Mazzone, \{Peter J.\} and Bach, \{Peter B.\} and Jacob Carey and Schonewolf, \{Caitlin A.\} and Katalin Bognar and Ahluwalia, \{Manmeet S.\} and Marcia Cruz-Correa and David Gierada and Sonali Kotagiri and Kathryn Lloyd and Fabien Maldonado and Ortendahl, \{Jesse D.\} and Sequist, \{Lecia V.\} and Silvestri, \{Gerard A.\} and Nichole Tanner and Thompson, \{Jeffrey C.\} and Anil Vachani and Wong, \{Kwok Kin\} and Zaidi, \{Ali H.\} and Joseph Catallini and Ariel Gershman and Keith Lumbard and Millberg, \{Laurel K.\} and Jeff Nawrocki and Carter Portwood and Aakanksha Rangnekar and Sheridan, \{Carolina Campos\} and Niti Trivedi and Tony Wu and Yuhua Zong and Lindsey Cotton and Allison Ryan and Christopher Cisar and Alessandro Leal and Nicholas Dracopoli and Scharpf, \{Robert B.\} and Velculescu, \{Victor E.\} and Pike, \{Luke R.G.\}",

note = "Publisher Copyright: {\textcopyright}2024 The Authors; Published by the American Association for Cancer Research.",

year = "2024",

month = nov,

day = "1",

doi = "10.1158/2159-8290.CD-24-0519",

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T1 - Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

AU - Mazzone, Peter J.

AU - Bach, Peter B.

AU - Carey, Jacob

AU - Schonewolf, Caitlin A.

AU - Bognar, Katalin

AU - Ahluwalia, Manmeet S.

AU - Cruz-Correa, Marcia

AU - Gierada, David

AU - Kotagiri, Sonali

AU - Lloyd, Kathryn

AU - Maldonado, Fabien

AU - Ortendahl, Jesse D.

AU - Sequist, Lecia V.

AU - Silvestri, Gerard A.

AU - Tanner, Nichole

AU - Thompson, Jeffrey C.

AU - Vachani, Anil

AU - Wong, Kwok Kin

AU - Zaidi, Ali H.

AU - Catallini, Joseph

AU - Gershman, Ariel

AU - Lumbard, Keith

AU - Millberg, Laurel K.

AU - Nawrocki, Jeff

AU - Portwood, Carter

AU - Rangnekar, Aakanksha

AU - Sheridan, Carolina Campos

AU - Trivedi, Niti

AU - Wu, Tony

AU - Zong, Yuhua

AU - Cotton, Lindsey

AU - Ryan, Allison

AU - Cisar, Christopher

AU - Leal, Alessandro

AU - Dracopoli, Nicholas

AU - Scharpf, Robert B.

AU - Velculescu, Victor E.

AU - Pike, Luke R.G.

PY - 2024/11/1

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DO - 10.1158/2159-8290.CD-24-0519

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AN - SCOPUS:85202670542

SN - 2159-8274

VL - 14

SP - 2224

EP - 2242

JO - Cancer Discovery

JF - Cancer Discovery

IS - 11

ER -

Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection

ASJC Scopus Subject Areas

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