Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group

Brian M Alexander, Paul D Brown; Manmeet Ahluwalia; Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeffrey S Wefel, Eudocia Q Lee, Patrick Y Wen, Response Assessment in Neuro-Oncology (RANO) group

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group

Brian M Alexander, Paul D Brown, Manmeet Ahluwalia, Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeffrey S Wefel, Eudocia Q Lee, Patrick Y Wen, Response Assessment in Neuro-Oncology (RANO) group

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	The Lancet. Oncology
Volume	19
State	Published - Jan 2018

Disciplines

Medicine and Health Sciences

Cite this

Paul D Brown, B. M. A., Ahluwalia, M., & Response Assessment in Neuro-Oncology (RANO) group, H. A. B. G. B. S. M. C. L. E. G. S. N. K. D. R. M. M. P. M. R. S. J. H. S. M. J. V. D. B. M. A. V. J. S. W. E. Q. L. P. Y. W. (2018). Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group. The Lancet. Oncology, 19.

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group. / Paul D Brown, Brian M Alexander,; Ahluwalia, Manmeet; Response Assessment in Neuro-Oncology (RANO) group, Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeffrey S Wefel, Eudocia Q Lee, Patrick Y Wen,.
In: The Lancet. Oncology, Vol. 19, 01.2018.

Research output: Contribution to journal › Article › peer-review

Paul D Brown, Brian M Alexander, ; Ahluwalia, Manmeet ; Response Assessment in Neuro-Oncology (RANO) group, Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeffrey S Wefel, Eudocia Q Lee, Patrick Y Wen,. / Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group. In: The Lancet. Oncology. 2018 ; Vol. 19.

@article{d6811bddee994208978f745d4cda9f94,

title = "Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group",

author = "\{Paul D Brown\}, \{Brian M Alexander,\} and Manmeet Ahluwalia and \{Response Assessment in Neuro-Oncology (RANO) group\}, \{Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeffrey S Wefel, Eudocia Q Lee, Patrick Y Wen,\}",

note = "The goals of therapeutic and biomarker development form the foundation of clinical trial design, and change considerably from early-phase to late-phase trials. From these goals, decisions on specific clinical trial design elements, such as endpoint selection and statistical approaches, are formed. W ...",

year = "2018",

month = jan,

language = "American English",

volume = "19",

journal = "The Lancet. Oncology",

}

TY - JOUR

T1 - Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group

AU - Paul D Brown, Brian M Alexander,

AU - Ahluwalia, Manmeet

AU - Response Assessment in Neuro-Oncology (RANO) group, Hidefumi Aoyama, Brigitta G Baumert, Susan M Chang, Laurie E Gaspar, Steven N Kalkanis, David R Macdonald, Minesh P Mehta, Riccardo Soffietti, John H Suh, Martin J van den Bent, Michael A Vogelbaum, Jeff

N1 - The goals of therapeutic and biomarker development form the foundation of clinical trial design, and change considerably from early-phase to late-phase trials. From these goals, decisions on specific clinical trial design elements, such as endpoint selection and statistical approaches, are formed. W ...

PY - 2018/1

Y1 - 2018/1

UR - https://pubmed.ncbi.nlm.nih.gov/29304360/

M3 - Article

VL - 19

JO - The Lancet. Oncology

JF - The Lancet. Oncology

ER -

Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group

Disciplines

Other files and links

Cite this