Anti-GM2 monoclonal antibodies induce necrosis in GM2-rich cultures of a human glioma cell line

TY - JOUR

T1 - Anti-GM2 monoclonal antibodies induce necrosis in GM2-rich cultures of a human glioma cell line

AU - D D Bigner, R Bjerkvig, O Engebraaten, O D Laerum, P Fredman, L Svennerholm, C J Wikstrand,

AU - Vrionis, Frank

N1 - The effects of four anti-GM2 monoclonal antibodies (DMAb-1, DMAb-2, DMAb-3, and DMAb-5) were studied on spheroid cultures from a human glioma cell line (D-54 MG) that is known to express high levels of GM2. The spheroids developed central necrosis 48 h after antibody exposures at concentrations grea ...

PY - 1991/9

Y1 - 1991/9

UR - https://pubmed.ncbi.nlm.nih.gov/1873810/

M3 - Article

VL - 51

JO - Cancer research

JF - Cancer research

ER -