@article{6026c824d08a4d85ab89650bc67a1d23,
title = "Advances in translational research provide a rationale for clinical re-evaluation of high-dose radiotherapy for glioblastoma",
author = "Carsten Nieder and Mehta, \{Minesh P.\}",
note = "Despite maximal surgical resection, postoperative radiotherapy and chemotherapy, the median survival of patients with glioblastoma (GBM) is only approximately 10-15 months. Older data in the literature support a radiation dose-survival relationship, and the predominant pattern of relapse is local, and yet, randomised dose-escalation trials have failed to improve survival, and the current standard of care remains 60 Gy in 30 fractions as well as chemotherapy.",
year = "2011",
month = mar,
day = "1",
doi = "10.1016/j.mehy.2010.11.005",
language = "American English",
volume = "76",
journal = "Medical Hypotheses",
}