Projects per year
Personal profile
About
Reshma Mahtani, D.O., is a medical oncologist at Miami Cancer Institute and chief of breast medical oncology for Baptist Health Wellness and Medical Complex. Dr. Mahtani’s practice is limited to the treatment of breast cancer. Prior to joining Miami Cancer Institute in 2022, Dr. Mahtani worked as an associate professor of medicine and co-leader of the Breast Cancer Site Disease Group at the University of Miami Miller School of Medicine. She was also the director of community outreach. Dr. Mahtani is an active clinical researcher, helping bring novel breast cancer treatments and clinical trials to patients in South Florida. She has made significant scientific and clinical practice contributions with numerous first-author publications in peer-reviewed journals. She is a nationally recognized thought leader in breast cancer and has presented her cancer research findings at cancer conferences worldwide. She has received funding from numerous organizations. Dr. Mahtani served on national committees to recognize cancer clinics that offer quality care across the country. She is involved in several initiatives that enhance patients’ access to healthcare, as well as community collaborations for education and advocacy. She founded a medical education initiative to ensure that physicians in South Florida know about the latest cancer treatments and can provide evidence-based care. Though she is a passionate researcher, Dr. Mahtani most enjoys spending time with her patients. She believes it is a privilege to be by their side, teaching them about their breast cancer and their treatment options. She strives to help every patient find hope through clinical trials and the latest immunotherapies and targeted therapies for breast cancer.
Related documents
Education/Academic qualification
Fellow, St.Vincents Catholic Medical Center
2004 → 2007
Resident, St.Vincents Catholic Medical Center
2002 → 2004
Greenwich Hospital, Internship, Yale University
2001 → 2002
Doctor, University of New England
… → 2001
Master of Science, University of Connecticut
… → 1997
Bachelor of Arts, Mount Holyoke College
… → 1994
External positions
Breast Program Director, Deerfield Beach
Jan 1 2019 → Jan 1 2021
Director of Community Outreach, University of Miami
Jan 1 2019 → Jan 1 2021
Associate Professor of Medicine / Co-Leader of Breast Cancer Site Disease Group, University of Miami
Jan 1 2010 → Jan 1 2021
Hematologist/Medical Oncologist / Director of Clinical Research, Boca Raton Regional Hospital
Jan 1 2007 → Jan 1 2010
Physician, Boca Raton Regional Hospital
Jan 1 2007 → Jan 1 2017
Physician, Delray Hospital
Jan 1 2007 → Jan 1 2010
Physician, West Boca Hospital
Jan 1 2007 → Jan 1 2010
Emergency Medical Technician, Rocky Hill Ambulance Association
Jan 1 1995 → Jan 1 1997
Research Assistant, University of Connecticut
Jan 1 1995 → Jan 1 1997
Research Assistant, Massachusetts General Hospital
Jan 1 1994 → Jan 1 1995
Pharmaceutical Technician, Cromwell Pharmacy
Jan 1 1989 → Jan 1 1994
Disciplines
- Medicine and Health Sciences
Projects
- 14 Finished
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Multimodal and temporal deep learning for designing optimal breast cancer treatment plans.
Abdel-Mottaleb, P. I. M. (CoI) & Mahtani, R. (CoI)
University of Miami, Sylvester Comprehensive Cancer Center
1/1/21 → 1/1/22
Project: Research project
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Prospective Observational Study of Mobile App-Based Patient-Reported Outcomes in Advanced Breast Cancer
Mahtani, R. (PI)
1/1/17 → 1/1/21
Project: Research project
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Measuring the Impact of MammaPrint on Adjuvant and Neoadjuvant Treatment in Breast Cancer Patients: A Prospective Registry (IMPACt)
Mahtani, R. (PI)
1/1/16 → 1/1/20
Project: Research project
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MONA-7: A Phase III Randomized, Double-blind, placebo-controlled study of MONA-7: LEE011 or Placebo in Combination with Tamoxifen and Goserelin or a Non-Steroidal Aromatase Inhibitor (NSAI) and Goserelin for the Treatment of Premenopausal Women with Hormone Receptor Positive, HER 2-Negative, Advanced Breast Cancer
Mahtani, R. (PI)
1/1/15 → 1/1/18
Project: Research project
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Circulating tumor cells dynamics after CDK4/6 inhibitor for hormone-receptor positive metastatic breast cancer: a biomarker analysis from the PACE phase II study
Gerratana, L., Reduzzi, C., Ren, Y., Jeselsohn, R., Mahtani, R. L., Ma, C. X., DeMichele, A., Meisel, J. L., Miller, K., Abdou, Y., Riley, E. C., Qamar, R., Sharma, P., Reid, S. A., Ko, N., Liu, Y., Gauthier, E., Burstein, H. J., DeMeo, M. & Tolaney, S. M. & 3 others, , Aug 25 2025, (E-pub ahead of print) In: Clinical cancer research : an official journal of the American Association for Cancer Research.Research output: Contribution to journal › Article › peer-review
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Circulating tumor DNA mutational landscape and dynamics after progression on a CDK4/6 inhibitor in the PACE phase II trial for metastatic HR-positive/HER2-negative breast cancer
Jeselsohn, R., Fu, J., Ren, Y., Mahtani, R., Ma, C., DeMichele, A., Cristofanilli, M., Meisel, J., Miller, K. D., Abdou, Y., Riley, E. C., Qamar, R., Sharma, P., Reid, S., Ko, N., Liu, Y., Gauthier, E., Burstein, H. J., DeMeo, M. & Regan, M. & 2 others, , Aug 2025, In: ESMO open. 10, 8, 105506.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparison of trastuzumab deruxtecan and sacituzumab govitecan in HER2-negative metastatic breast cancer: a large real-world data analysis
Sledge, G. W. J., Xiu, J., Solzak, J. P., Ribeiro, J., Mahtani, R. L., Lustberg, M. B., Oberley, M. J., Radovich, M. & Spetzler, D., Dec 2025, In: Breast Cancer Research. 27, 1, 144.Research output: Contribution to journal › Article › peer-review
Open Access -
Expert consensus on treating HR+/HER2- metastatic breast cancer based on real-world practice patterns observed in the RETRACT survey of US oncologists
Rugo, H. S., Bardia, A., Gradishar, W. J., Hamilton, E. P., Hurvitz, S. A., Jhaveri, K., Mahtani, R. & Tolaney, S. M., Aug 2025, In: Breast. 82, 104485.Research output: Contribution to journal › Article › peer-review
Open Access -
Human Epidermal Growth Factor Receptor 2-Positive (HER2+) Early Breast Cancer Treatment and Outcomes by Risk of Recurrence: A Retrospective US Electronic Health Records Study
Mahtani, R., Collin, S. M., Tan, Z., Shah, C. H., Adeyemi, B., Davies, S., John, E. & Vidal, G., Jun 2025, In: Cancers. 17, 11, 1848.Research output: Contribution to journal › Article › peer-review
Open Access
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American Cancer Society, ResearcHERS Medical Advisory Board (External organization)
Mahtani, R. (Member)
Jan 1 2020 → …Activity: Membership › Membership of network
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Living Beyond Breast Cancer Medical Advisory Board (External organization)
Mahtani, R. (Member)
Jan 1 2019 → …Activity: Membership › Membership of network
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Institutional Representative University of Miami
Mahtani, R. (Member)
Jan 1 2018 → Jan 1 2021Activity: Other
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Institutional Representative University of Miami
Mahtani, R. (Member)
Jan 1 2018 → Jan 1 2021Activity: Other
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Florida Society of Clinical Oncology (FLASCO) Board of Directors (External organization)
Mahtani, R. (Member)
Jan 1 2017 → …Activity: Membership › Membership of network
Prizes
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Graduated with High Honor (Mount Holyoke College), 1994
Mahtani, R. (Recipient), 1994
Prize: Prize (including medals and awards)
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Howard Hughes Research Fellowship, 1994 – 1995
Mahtani, R. (Recipient), 1994
Prize: Prize (including medals and awards)
-
Sigma Phi Honor Society, 1997
Mahtani, R. (Recipient), 1997
Prize: Prize (including medals and awards)